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Urine DNA methylation assay enables early detection and recurrence monitoring for bladder cancer

20 Aug 2020

Abstract excerpt

BACKGROUNDCurrent methods for the detection and surveillance of bladder cancer (BCa) are often invasive and/or possess suboptimal sensitivity and specificity, especially in early-stage, minimal, and residual tumors.METHODSWe developed an efficient method, termed utMeMA, for the detection of urine tumor DNA methylation at multiple genomic regions by MassARRAY. We identified the BCa-specific methylation markers by...

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Share to Bladder and Urothelial Cancer Treatments
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PMID: 32817589
DOI: 10.1172/jci139597

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