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Antibody-mediated broad sarbecovirus neutralization through ACE2 molecular mimicry

2021-10-14

Abstract excerpt

Understanding broadly neutralizing sarbecovirus antibody responses is key to developing countermeasures effective against SARS-CoV-2 variants and future spillovers of other sarbecoviruses. Here we describe the isolation and characterization of a human monoclonal antibody, designated S2K146, broadly neutralizing viruses belonging to all three sarbecovirus clades known to utilize ACE2 as entry receptor and protectin...

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Identifiers and source

Literature Corpus work
071081fb-1ad2-5ce4-8c99-d1d42d083f9c
DOI
10.1101/2021.10.13.464254
Open publication

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Antibody-mediated broad sarbecovirus neutralization through ACE2 molecular mimicryDOI 10.1101/2021.10.13.464254
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