Article

A Bacterial Signaling Network Controls Antibiotic Resistance by Regulating Anaplerosis of 2-oxoglutarate

2020-10-23

Abstract excerpt

Antibiotic resistance has become a global threat. In addition to acquiring resistance via horizontal gene transfer, bacteria can evade killing by temporarily modifying their cell envelope to prevent antibiotic-bacterial interactions. A critical gap in knowledge is how bacteria balance the metabolic needs of altering the cell envelope with the constant need to generate energy. Cross-regulation between two signaling...

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Literature Corpus work: 06fb668e-0556-5298-b17a-7af2a6a6ce01
DOI: 10.1101/2020.10.22.351270

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