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Metabolism-Based Biomarkers for Rapid Phenotypic Antibiotic Susceptibility Testing.

Advanced science (Weinheim, Baden-Wurttemberg, Germany) - 1 Jun 2026

Yu Sha, Bayinqiaoge, Lu Xi, Wang Xin, Wang Rongfeng, Li Yi, Tang Shi-Yang, Zhang Chengchen

Abstract excerpt

The accelerating global crisis of antimicrobial resistance (AMR) demands rapid and accurate methods for antibiotic susceptibility testing (AST). Conventional phenotypic assays remain the gold standard but are hindered by long culture times, while genotypic tests cannot reliably predict phenotypic resistance. In recent years, metabolism-based AST has emerged as a promising alternative, enabling the rapid detection...

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PMID: 42095490
DOI: 10.1002/advs.75553
PMCID: PMC13271646

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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