Article
The IκB family member Bcl-3 coordinates the pulmonary defense against Klebsiella pneumoniae infection.
Journal of immunology (Baltimore, Md. : 1950) - 15 Feb 2011
Pène Frédéric, Paun Andrea, Sønder Søren Ulrik, Rikhi Nimisha, Wang Hongshan, Claudio Estefania, Siebenlist Ulrich
Abstract excerpt
Bcl-3 is an atypical member of the IκB family that has the potential to positively or negatively modulate nuclear NF-κB activity in a context-dependent manner. Bcl-3's biologic impact is complex and includes roles in tumorigenesis and diverse immune responses, including innate immunity. Bcl-3 may...
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