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The Putative Oncoprotein Bcl-3 Induces Cyclin D1 To Stimulate G<sub>1</sub> Transition

1 Dec 2001

Abstract excerpt

Bcl-3 is a distinctive member of the IkappaB family of NF-kappaB inhibitors because it can function to coactivate transcription. A potential involvement of Bcl-3 in oncogenesis is highlighted by the fact that it was cloned due to its location at a breakpoint junction in some cases of human B-cell chronic lymphocytic leukemia and that it is highly expressed in human breast tumor tissue. To analyze the effects of...

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PMID: 11713278
DOI: 10.1128/mcb.21.24.8428-8436.2001

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