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Mouse brain organoids model <i>in vivo</i> neurodevelopment and function and capture differences to human

2024-12-21

Abstract excerpt

In the last decade since their emergence, brain organoids have offered an increasingly popular and powerful model for the study of early development and disease in humans. These 3D stem cell-derived models exist in a newer space at the intersection of in vivo and 2D in vitro models. Functional benchmarking has so far remained largely uncharacterised however, leaving the extent to which these models may accuratel...

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Literature Corpus work
2e539239-537e-5a1e-b75c-9fe624df1b3e
DOI
10.1101/2024.12.21.629881
Open publication

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Mouse brain organoids model <i>in vivo</i> neurodevelopment and function and capture differences to humanDOI 10.1101/2024.12.21.629881
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