Data- and knowledge-derived functional landscape of human solute carriers

Abstract excerpt

Research on the understudied solute carrier (SLC) superfamily of membrane transporters would greatly profit from a comprehensive knowledgebase, synthesizing data and knowledge on different aspects of SLC function. We consolidated multi-omics data sets with selected curated information from the public domain, such as structure prediction, substrate annotation, disease association and subcellular localization. This...

Topics

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• Amino Acid Enzymes and Metabolism
• Biomedical Research
• Drug Discovery
• Drug Transport and Resistance Mechanisms
• Gene Expression
• Machine Learning in Bioinformatics
• RNA and protein synthesis mechanisms
• Trace Elements in Health

Identifiers and source

Literature Corpus work

067967ee-6eb7-5611-9614-8fa39b0dcda4

DOI

10.1101/2024.10.14.618155