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Article

Systematic in silico discovery of novel solute carrier-like proteins from proteomes

28 Jul 2022

Abstract excerpt

Solute carrier (SLC) proteins represent the largest superfamily of transmembrane transporters. While many of them play key biological roles, their systematic analysis has been hampered by their functional and structural heterogeneity. Based on available nomenclature systems, we hypothesized that many as yet unidentified SLC transporters exist in the human genome, which await further systematic analysis. Here, we...

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PMID: 35901096
DOI: 10.1371/journal.pone.0271062

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