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A phylogenetic analysis between humans and D. melanogaster: A repertoire of solute carriers in humans and flies

19 Oct 2021

Abstract excerpt

The solute carrier (SLC) superfamily is the largest group of transporters in humans, with the role to transport solutes across plasma membranes. The SLCs are currently divided into 65 families with 430 members. Here, we performed a detailed mining of the SLC superfamily and the recent annotated family of "atypical" SLCs in human and D. melanogaster using Hidden Markov Models and PSI-BLAST. Our analyses identified...

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PMID: 34673204
DOI: 10.1016/j.gene.2021.146033

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