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The <i>kpc-1</i> 3’UTR facilitates dendritic transport and translation of mRNAs for dendrite arborization of a mechanosensory neuron important for male courtship

2021-08-05

Abstract excerpt

<h4>Summary</h4> A recently reported Schizophrenia-associated genetic variant in the 3’UTR of the human furin gene, a homolog of C. elegans kpc-1 , highlights an important role of the furin 3’UTR in neuronal development( 1 ). We isolate three kpc-1 mutants that display abnormal dendrite arborization in PVD neurons and defective male mating behaviors. We show that the kpc-1 3’UTR participates in dendrite branc...

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Identifiers and source

Literature Corpus work
06273928-c7ce-5b46-8f23-82baff03dcee
DOI
10.1101/2021.08.03.453128
Open publication

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The <i>kpc-1</i> 3’UTR facilitates dendritic transport and translation of mRNAs for dendrite arborization of a mechanosensory neuron important for male courtshipDOI 10.1101/2021.08.03.453128
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