Article

The mammalian Kalrn locus gives rise to several novel long non-coding RNAs

2022-02-15

Abstract excerpt

<title>Abstract</title> <p>The <italic>KALRN</italic> gene encodes several multi-domain protein isoforms that localise to neuronal synapses, and play dynamic roles in shaping axonal outgrowth, dendrite morphology and dendritic spine re-modelling. The genomic locus is implicated in several neurodevelopmental and neuropsychiatric diseases including autism, schizophrenia and bipolar disease. Mutations in the coding...

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Literature Corpus work: f3917297-0742-5cff-ba87-0b854fe6e863
DOI: 10.21203/rs.3.rs-1187363/v2

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