Article

Modelling the spatiotemporal dynamics of senescent cells in wound healing, chronic wounds, and fibrosis

2024-07-08

Abstract excerpt

Cellular senescence is known to drive age-related pathology through the senescence-associated secretory phenotype (SASP). However, it also plays important physiological roles such as cancer suppression, embryogenesis and wound healing. Wound healing is a tightly regulated process which when disrupted results in conditions such as fibrosis and chronic wounds. Senescent cells appear during the proliferation phase of...

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Literature Corpus work: 05d134b5-e5e2-555c-b22a-0f62f42c90ec
DOI: 10.1101/2024.07.04.602041

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