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Article

Modeling of the Senescence-Associated Phenotype in Human Skin Fibroblasts.

International journal of molecular sciences - 27 Jun 2022

Gerasymchuk Marta, Robinson Gregory Ian, Kovalchuk Olga, Kovalchuk Igor

Abstract excerpt

Modern understanding of aging is based on the accumulation of cellular damage during one's life span due to the gradual deterioration of regenerative mechanisms in response to the continuous effect of stress, lifestyle, and environmental factors, followed by increased morbidity and mortality. Simultaneously, the number of senescent cells accumulate exponentially as organisms age. Cell culture models are valuable...

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Source

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Identifiers

PMID: 35806127
DOI: 10.3390/ijms23137124
PMCID: PMC9266450

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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