Article

BRCA1 novel variation V1736D and in silico analysis of SNP Q356R in Sudanese patients with breast cancer

2018-01-24

Abstract excerpt

<h4>Background: </h4> : Breast cancer (BC) remains one of the leading causes of death in women worldwide. The BRCA1 deleterious mutation has a significant role in developing BC, and the risk has been estimated to be 46–87%. Many studies emphasize the need for mining BRCA1 gene mutations that might have a role in BC pathogenesis and could affect early disease onset. This study was conducted to screen for possible...

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Literature Corpus work: 05af9bbb-bfa4-56e9-a965-05cc2d936ad8
DOI: 10.12688/f1000research.11395.4

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