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Prevalence of specific and recurrent/founder pathogenic variants in BRCA genes in breast and ovarian cancer in North Africa.

BMC cancer - 25 Feb 2022

ElBiad Oubaida, Laraqui Abdelilah, El Boukhrissi Fatima, Mounjid Chaimaa, Lamsisi Maryame, Bajjou Tahar, Elannaz Hicham, Lahlou Amine Idriss, Kouach Jaouad, Benchekroune Khadija, Oukabli Mohammed, Chahdi Hafsa, Ennaji Moulay Mustapha, Tanz Rachid, Sbitti Yassir, Ichou Mohammed, Ennibi Khalid, Badaoui Bouabid, Sekhsokh Yassine

Abstract excerpt

BACKGROUND: Elucidation of specific and recurrent/founder pathogenic variants (PVs) in BRCA (BRCA1 and BRCA2) genes can make the genetic testing, for breast cancer (BC) and/or ovarian cancer (OC), affordable for developing nations. METHODS: To establish the knowledge about BRCA PVs and to determine the prevalence of the specific and recurrent/founder variants in BRCA genes in BC and/or OC women in North Africa, a...

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Identifiers

PMID: 35216584
DOI: 10.1186/s12885-022-09181-4
PMCID: PMC8876448

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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