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Whole exome sequencing reveals a combination of rare high and low penetrance variants that correlates with familial breast cancer relative risk

2020-07-17

Abstract excerpt

<title>Abstract</title> <p><bold>Background: </bold>Genetic risk factors of breast cancer are very heterogeneous and complex. They vary according to the familial relative risk, the age of cancer diagnosis of the index case and the age of the affected relatives.<bold>Objectives: </bold>We aimed to investigate and identify simultaneously all rare pathogenic and common variants in unrelated BC cases with different r...

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Literature Corpus work
02d2887b-3c70-5ec6-881a-57eaeda69a86
DOI
10.21203/rs.3.rs-22989/v2
Open publication

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Whole exome sequencing reveals a combination of rare high and low penetrance variants that correlates with familial breast cancer relative riskDOI 10.21203/rs.3.rs-22989/v2
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