Article

Combined Therapeutic Strategies Based on the Inhibition of Non-Oncogene Addiction to Improve Tumor Response in EGFR and KRAS Mutant NSCLC

2024-11-19

Abstract excerpt

<h4>Background: </h4> Oncogene-driven NSCLC are usually treated with targeted therapies using tyrosine kinase inhibitors (TKIs) to inhibit oncogene downstream signaling pathways thus affecting tumor survival and proliferation. EGFR and KRAS mutant NSCLC are the most represented subtypes and they are treated in clinical practice with oncogene-targeting drugs in first and second line, respectively. Unfortunately, th...

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Literature Corpus work: 05a7f68b-9ad6-5a9c-b895-b02ccae8e25b
DOI: 10.20944/preprints202411.1291.v1

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