Article

Hypusinated and unhypusinated isoforms of eIF5A exert distinct effects in models of pancreas development and function

2024-10-27

Abstract excerpt

Hypusination of eukaryotic translation initiation factor 5A (eIF5A) is essential for its role in translation elongation and termination. Although the function of hypusinated eIF5A (eIF5A Hyp ) in cellular proliferation is well-characterized, the role of its unhypusinated form (eIF5A Lys ) remains unclear. We hypothesized that eIF5A Lys exerts independent effects on cellular replication and metabolism distinct f...

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Literature Corpus work: 055c2798-ecab-5b9d-bf71-d597edb193af
DOI: 10.1101/2024.10.27.620489

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Hypusinated and unhypusinated isoforms of eIF5A exert distinct effects in models of pancreas development and functionDOI 10.1101/2024.10.27.620489Read

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