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Article

Deoxyhypusine synthase haploinsufficiency attenuates acute cytokine signaling.

Cell cycle (Georgetown, Tex.) - 1 Apr 2011

Templin Andrew T, Maier Bernhard, Nishiki Yurika, Tersey Sarah A, Mirmira Raghavendra G

Abstract excerpt

Deoxyhypusine synthase (DHS) catalyzes the post-translational formation of the amino acid hypusine. Hypusine is unique to the eukaryotic translational initiation factor 5A (eIF5A), and is required for its functions in mRNA shuttling, translational elongation, and stress granule formation. In rece...

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Identifiers

PMID: 21389784
DOI: 10.4161/cc.10.7.15206
PMCID: PMC3100881

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-21389784-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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Deoxyhypusine synthase haploinsufficiency attenuates acute cytokine signaling.PMID 21389784Read ↗

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