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Novel R-type Lectin Domain-Containing Cytotoxins Comprise a Family of Virulence-Modifying Proteins in Pathogenic <i>Leptospira</i>

2020-05-13

Abstract excerpt

Leptospirosis is a globally important neglected zoonotic disease subject to both small scale outbreaks and weather-driven, large-scale epidemics. Due to gaps in our understanding of Leptospira biology, pathogenetic mechanisms of leptospirosis remain largely unknown. Previous data suggest that a gene family, PF07598, unique amongst most known bacterial pathogens and encoding so-called “Virulence-Modifying (VM)” pr...

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Literature Corpus work
05570b1e-8449-51de-acd0-e6dbb6e407f3
DOI
10.1101/2020.05.13.094169
Open publication

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