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Leptospiral Immunoglobulin-Like Domain Proteins: Roles in Virulence and Immunity

8 Jan 2021

Abstract excerpt

The virulence mechanisms required for infection and evasion of immunity by pathogenic Leptospira species remain poorly understood. A number of L. interrogans surface proteins have been discovered, lying at the interface between the pathogen and host. Among these proteins, the functional properties of the Lig (leptospiral immunoglobulin-like domain) proteins have been examined most thoroughly. LigA, LigB, and LigC...

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PMID: 33488581
DOI: 10.3389/fimmu.2020.579907

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