Article

Transient loss of Polycomb components induces an epigenetic cancer fate

2023-01-04

Abstract excerpt

<h4>Summary</h4> Cell fate depends on genetic, epigenetic and environmental inputs that are interconnected, making it difficult to disentangle their respective contributions to cell fate decisions 1-3 , and epigenetic reprogramming is a major contributor to tumor plasticity and adaptation 4-6 . Although cancer initiation and progression are generally associated with the accumulation of somatic mutations 7,8 ,...

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Literature Corpus work: 0520b967-c5f0-566f-8e24-31e57167f5c9
DOI: 10.1101/2023.01.04.522799

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