Article

Polymorphisms in HIV-1 <i>nef</i> are associated with plasma concentration of biomarkers of endothelial activation

2022-10-10

Abstract excerpt

Infection with HIV is associated with an increased risk of cardiovascular disease (CVD), which may be mediated by the effect of the viral proteins, Nef and Tat, on inflammation and endothelial activation. The viral genes coding for Nef and Tat contain numerous polymorphisms, which we hypothesised may be differentially associated with endothelial activation. Therefore, our aim was to assess the association of these...

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Literature Corpus work: 05005ac8-4013-5616-8e0c-e1ebe1978a98
DOI: 10.1101/2022.10.10.511468

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