Article
Immune activation in the course of HIV-1 infection: Causes, phenotypes and persistence under therapy.
HIV medicine - 1 Feb 2016
Younas M, Psomas C, Reynes J, Corbeau P
Abstract excerpt
Systemic immune activation is a striking consequence of HIV-1 infection. Even in virologically suppressed patients, some hyperactivity of the immune system and even of the endothelium and of the coagulation pathway may persist. Apart from immune deficiency, this chronic activation may contribute to various morbidities including atherothrombosis, neurocognitive disorders, liver steatosis and osteoporosis, which...
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