Article

Profiling of epithelial functional states and fibroblast phenotypes in hormone therapy-naïve localised prostate cancer

2024-10-28

Abstract excerpt

Localised prostate cancers (PCa) are heterogeneous and multifocal, with diverse outcomes. Current prognostic methods are epithelium-centric, overlooking the complex cellular landscape within the tumour microenvironment (TME), which remains incompletely characterised. We performed a comprehensive analysis of cancerous and adjacent-benign cores from 24 patients with hormone therapy-naïve localised PCa using single-c...

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Literature Corpus work: 04f9e4c1-aaf5-5fca-aed2-cba1ae139dd7
DOI: 10.1101/2024.10.23.619925

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