Article

Rotavirus as an Expression Platform of the SARS-CoV-2 Spike Protein

2021-02-18

Abstract excerpt

Rotavirus, a segmented double-stranded RNA virus, is a major cause of acute gastroenteritis in young children. The introduction of live oral rotavirus vaccines has reduced the incidence of rotavirus disease in many countries. To explore the possibility of establishing a combined rotavirus-SARS-CoV-2 vaccine, we generated recombinant (r)SA11 rotaviruses with modified segment 7 RNAs that contained coding sequences f...

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Literature Corpus work: 04f40413-5d57-5759-8db4-cc2ec5095f14
DOI: 10.1101/2021.02.18.431835

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