Article

The nonlinearity of regulation in biological networks

2021-12-23

Abstract excerpt

<h4>ABSTRACT</h4> The extent to which the components of a biological system are (non)linearly regulated determines how amenable they are to therapy and control. To better understand this property termed ‘regulatory nonlinearity’, we analyzed a suite of 137 published Boolean network models, containing a variety of complex nonlinear regulatory interactions, using a probabilistic generalization of Boolean logic that...

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Literature Corpus work: 04e78ade-b1a6-5348-a08a-b0eaef450498
DOI: 10.1101/2021.12.22.473903

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