Article

The lipid flippase ATP10B enables cellular lipid uptake under stress conditions

2023-06-01

Abstract excerpt

Pathogenic ATP10B variants have been described in patients with Parkinson’s disease and dementia with Lewy body disease, and we previously established ATP10B as a late endo-/lysosomal lipid flippase transporting both phosphatidylcholine (PC) and glucosylceramide (GluCer) from the lysosomal exoplasmic to cytoplasmic membrane leaflet. Since several other lipid flippases regulate cellular lipid uptake, we here examin...

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Literature Corpus work: 04c10420-edf0-5a89-8e6e-4c6aee96837a
DOI: 10.1101/2023.06.01.543059

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