Article
Age-related susceptibility to grey matter demyelination and neurodegeneration is associated with meningeal neutrophil accumulation in an animal model of Multiple Sclerosis
2021-12-24
Abstract excerpt
People living with multiple sclerosis (MS) experience episodic central nervous system (CNS) white matter lesions instigated by autoreactive T cells. With age, MS patients show evidence of grey matter demyelination and experience devastating non-remitting symptomology. What drives progression is unclear and has been hampered by the lack of suitable animal models. Here we show that passive experimental autoimmune en...
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Identifiers and source
- Literature Corpus work
- 0472dc56-df4a-55be-80fd-11a5957b62a6
- DOI
- 10.1101/2021.12.23.474008