Article

Probiotic Associated Therapeutic Curli Hybrids (PATCH)

2018-11-07

Abstract excerpt

There is an unmet need for new treatment methods for inflammatory bowel disease (IBD) that can reliably maintain remission without leading to detrimental side effects. Beneficial bacteria have been utilized as an alternative treatment for IBD albeit with low efficacy. We genetically engineered Escherichia coli Nissle 1917 (EcN) to create an anti-inflammatory fibrous matrix in situ . This matrix consists of EcN-p...

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Literature Corpus work: 0468852d-02a6-5fa1-98a9-341b6061d40b
DOI: 10.1101/464966

Open publication

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