Article

Effects of shear stress on NF-κB transcription factors in vascular endothelium

2011-01-01

Abstract excerpt

Atherosclerosis, a chronic inflammatory disease of arteries, occurs predominantly at regions of the arterial system that are exposed to disturbed patterns of blood flow. Blood flow influences the atherosclerosis by exerting shear stress on endothelial cells (ECs). Although the signalling pathways that activate pro-inflammatory NF-κB transcription factors are well defined, the regulation and physiological significa...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 041103ce-dd71-500f-9afd-455f9fbebf9c
DOI: 10.25560/6440

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Effects of shear stress on NF-κB transcription factors in vascular endotheliumDOI 10.25560/6440Read

Vascular endothelial responses to altered shear stress: Pathologic implications for atherosclerosisSemantic proximity Read

Distinct NF-kappaB regulation by shear stress through Ras-dependent IkappaBalpha oscillations: real-time analysis of flow-mediated activation in live cells.Semantic proximity Read

Hemodynamic shear stress and its role in atherosclerosis.Semantic proximity Read

Hemodynamics and endothelial cell biology in cardiovascular diseasesSemantic proximity Read

Flow shear stress and atherosclerosis: a matter of site specificity.Semantic proximity Read

Disturbed flow induces a sustained, stochastic NF-κB activation which may support intracranial aneurysm growth in vivoSemantic proximity Read

Hemodynamic shear stress and the endothelium in cardiovascular pathophysiology.Semantic proximity Read

Shear stress-initiated signaling and its regulation of endothelial function.Semantic proximity Read

Biomechanical factors and macrophages in plaque stability.Semantic proximity Read

The Role of Shear Stress in Atherosclerosis: Action Through Gene Expression and Inflammation?Semantic proximity Read

Fluid Mechanics, Arterial Disease, and Gene ExpressionSemantic proximity Read

Mechanotransduction of shear in the endothelium: Basic studies and clinical implicationsSemantic proximity Read