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Dissecting the Impact of USP21 on Mouse Lipid Metabolism and Identifying Polymorphism-Associated Hypercholesterolemia in Outpatients

2023-11-20

Abstract excerpt

USP21, a member of the ubiquitin protease family, plays a vital role in various biological functions. However, the effects of USP21 dysfunction have yet to be fully understood. Here, we generated Usp21 knockout (KO) mice and conducted microarray to identify genes that Usp21 regulates. Its results raised several genes based on their biological characteristics, and RT-qPCR confirmed their expression. KO mice exhibit...

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Literature Corpus work
040a7681-2361-59e6-abe7-ad156484b301
DOI
10.20944/preprints202311.1236.v1
Open publication

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Dissecting the Impact of USP21 on Mouse Lipid Metabolism and Identifying Polymorphism-Associated Hypercholesterolemia in OutpatientsDOI 10.20944/preprints202311.1236.v1
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