Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Role of USP13 in physiology and diseases

14 Sept 2022

Abstract excerpt

Ubiquitin specific protease (USP)-13 is a deubiquitinase that removes ubiquitin from substrates to prevent protein degradation by the proteasome. Currently, the roles of USP13 in physiology and pathology have been reported. In physiology, USP13 is highly associated with cell cycle regulation, DNA damage repair, myoblast differentiation, quality control of the endoplasmic reticulum, and autophagy. In pathology, it...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Autophagy in Disease and Therapy
Share to Genetics and Neurodevelopmental Disorders
Share to Ubiquitin and proteasome pathways

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 36188217
DOI: 10.3389/fmolb.2022.977122

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Role of USP13 in physiology and diseasesPMID 36188217Read ↗

Spotlights on ubiquitin-specific protease 12 (USP12) in diseases: from multifaceted roles to pathophysiological mechanismsSemantic proximity Read ↗

USP13: Multiple Functions and Target InhibitionSemantic proximity Read ↗

USP3 : Key deubiquitylation enzyme in human diseasesSemantic proximity Read ↗

USP5: Comprehensive insights into structure, function, biological and disease-related implications, and emerging therapeutic opportunitiesSemantic proximity Read ↗

Roles of ubiquitin-specific proteases in inflammatory diseasesSemantic proximity Read ↗

Emerging insights into HAUSP (USP7) in physiology, cancer and other diseasesSemantic proximity Read ↗

An Overview of the Deubiquitinase USP53: A Promising Diagnostic Marker and Therapeutic Target.Semantic proximity Read ↗

Cardiomyocyte-derived USP13 protects hearts from hypertrophy via deubiquitinating and stabilizing STAT1 in male miceSemantic proximity Read ↗

Structure and function of USP5: Insight into physiological and pathophysiological rolesSemantic proximity Read ↗

Unraveling the Immune Regulatory Functions of USP5: Implications for Disease TherapySemantic proximity Read ↗

The Multifaceted Roles of USP15 in Signal TransductionSemantic proximity Read ↗

Roles of USP9X in cellular functions and tumorigenesis (Review)Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.