Article

Investigating the potential role of USP18 in atherosclerosis by regulating cholesterol efflux based on bioinformatics analysis

2022-09-28

Abstract excerpt

<title>Abstract</title> <p><bold>Background</bold> Ubiquitin-specific protease 18 (USP18), also known as UBP43, is a member of the ubiquitin-specific protease family involved in suppressing viral activity and promoting tumor migration. Previous studies have shown that USP18 expression is upregulated in the patients with heart failure and USP18 is considered as a novel target for the treatment of heart failure. Ho...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: ab48a137-14ac-5d10-8a75-8ba8b7012891
DOI: 10.21203/rs.3.rs-2100870/v1

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Investigating the potential role of USP18 in atherosclerosis by regulating cholesterol efflux based on bioinformatics analysisDOI 10.21203/rs.3.rs-2100870/v1Read

Investigating the potential role of USP18 in atherosclerosis based on bioinformatics analysisSemantic proximity Read

The role of deubiquitinases in cardiovascular diseases: mechanisms and therapeutic implicationsSemantic proximity Read

Comprehensive analysis of ubiquitin‐specific protease 1 reveals its importance in hepatocellular carcinomaSemantic proximity Read

Role of USP13 in physiology and diseasesSemantic proximity Read

The ubiquitin-proteasome activity of macrophages involved in the rupture of atherosclerotic plaque based on bioinformatics analysisSemantic proximity Read

LINC01419/miR-132-3p/USP38 Axis Mediates High Glucose-Induced Ferroptosis in Vascular Endothelial CellsSemantic proximity Read

Dissecting the Impact of USP21 on Mouse Lipid Metabolism and Identifying Polymorphism-Associated Hypercholesterolemia in OutpatientsSemantic proximity Read

SORBS2 As A Molecular Target For Atherosclerosis In Patients With Familial HypercholesterolemiaSemantic proximity Read

USP11 promotes lipogenesis and tumorigenesis by regulating SREBF1 stability in hepatocellular carcinomaSemantic proximity Read

Deubiquitinase USP1 enhances CCAAT/enhancer-binding protein beta (C/EBPβ) stability and accelerates adipogenesis and lipid accumulationSemantic proximity Read

USP14 exhibits high expression levels in hepatocellular carcinoma and plays a crucial role in promoting the growth of liver cancer cells through the HK2/AKT/P62 axisSemantic proximity Read

USP18 Curbs the Progression of Metabolic Hypertension by Suppressing JAK/STAT PathwaySemantic proximity Read