Article

Allele-linked divergence in SlpA and TcdB drives distinct immune and cytotoxic responses that distinguish ST01 from non-ST01 strains in Clade 2 Clostridioides difficile

2025-08-08

Abstract excerpt

Among the five MLST clades that define the global population structure of the bacterial pathogen Clostridioides difficile, Clade 2 has received special attention due to the global spread, clinical severity, and hospital prevalence of ST01 strains. To identify features potentially contributing to the historically attributed higher virulence and epidemic potential of ST01 strains, we compared a range of phenotypic t...

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Literature Corpus work: 039981b0-aab6-5f2d-8685-66b53a000441
DOI: 10.1099/acmi.0.000994.v2

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