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Article

Epigenetic Aberrations in Multiple Myeloma

15 Oct 2020

Abstract excerpt

Multiple myeloma (MM) is a plasma cell dyscrasia characterized by proliferation of clonal plasma cells within the bone marrow. Several advances in defining key processes responsible for MM pathogenesis and disease progression have been made; and dysregulation of epigenetics, including DNA methylation and histone modification, has emerged as a crucial regulator of MM pathogenesis. In the present review article, we...

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PMID: 33076518
DOI: 10.3390/cancers12102996

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