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Article

Epigenetic regulatory mutations and epigenetic therapy for multiple myeloma.

Current opinion in hematology - 1 Jul 2017

Dupéré-Richer Daphné, Licht Jonathan D

Abstract excerpt

PURPOSE OF REVIEW: Next generation sequencing and large-scale analysis of patient specimens has created a more complete picture of multiple myeloma (MM) revealing that epigenetic deregulation is a prominent factor in MM pathogenesis. RECENT FINDINGS: Over half of MM patients have mutations in genes encoding epigenetic modifier enzymes. The DNA methylation profile of MM is related to the stage of the disease and...

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Identifiers

PMID: 28441149
DOI: 10.1097/MOH.0000000000000358
PMCID: PMC5767522

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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