Article

Protein expression derived from scRNA-seq reveals lupus-induced acceleration of immune aging

2026-05-11

Abstract excerpt

<title>Abstract</title> <p>Single-cell RNA sequencing (scRNA-seq) is widely established and excels at capturing transcriptional heterogeneity and signaling states. However, it lacks direct quantification of surface proteins, which are key determinants of immune cell identity and function. To enable protein-based characterization of immunophenotypic diversity in scRNA-seq data, we developed scEN, which employs a r...

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Literature Corpus work: 036c3eb3-aa12-5984-863f-41df1d666d7b
DOI: 10.21203/rs.3.rs-9418867/v1

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