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Integrated single-cell analysis unveils diverging immune features of COVID-19, influenza, and other community-acquired pneumonia

20 Aug 2021

Abstract excerpt

The exact immunopathophysiology of community-acquired pneumonia (CAP) caused by SARS-CoV-2 (COVID-19) remains clouded by a general lack of relevant disease controls. The scarcity of single-cell investigations in the broader population of patients with CAP renders it difficult to distinguish immune features unique to COVID-19 from the common characteristics of a dysregulated host response to pneumonia. We...

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PMID: 34424199
DOI: 10.7554/elife.69661

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