Article
Identifying proteins that bind to specific RNAs - focus on simple repeat expansion diseases.
Nucleic acids research - 2 Nov 2016
Jazurek Magdalena, Ciesiolka Adam, Starega-Roslan Julia, Bilinska Katarzyna, Krzyzosiak Wlodzimierz J
Abstract excerpt
RNA-protein complexes play a central role in the regulation of fundamental cellular processes, such as mRNA splicing, localization, translation and degradation. The misregulation of these interactions can cause a variety of human diseases, including cancer and neurodegenerative disorders. Recently, many strategies have been developed to comprehensively analyze these complex and highly dynamic RNA-protein...
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