Article

The Motor Neuron Disease Mouse Model hSOD1-G93A Presents a Non-canonical Profile of Senescence Biomarkers in the Spinal Cord

2020-12-23

Abstract excerpt

<title>Abstract</title> <p>Recent evidence demonstrates a pathological role for senescent cells in Alzheimer’s and Parkinson’s diseases. The present study aimed to show senescence mechanisms including senescence-associated secretory phenotype (SASP) in the familial amyotrophic lateral sclerosis (ALS) transgenic mouse model hSOD1-G93A. We evaluated, as senescence biomarkers, the expression of <italic>p16</italic>...

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Literature Corpus work: 033a21ae-49c0-5152-869a-26c9a2a615e5
DOI: 10.21203/rs.3.rs-131980/v1

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