Article

Dual role of an essential HtrA2/Omi protease in the human malaria parasite: maintenance of mitochondrial homeostasis and induction of apoptosis like cell death under cellular stress

2022-03-16

Abstract excerpt

HtrA family of serine protease is known to play role in mitochondrial homeostasis as well as in the programmed cell death. Mitochondrial homeostasis and metabolism are crucial for survival and propagation of malaria parasite within the host. Here we have functionally characterized a Plasmodium falciparum HtrA2 ( Pf HtrA2) protein, which harbours trypsin like protease activity that can be inhibited by its specifi...

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Literature Corpus work: 031a430a-b380-511b-8209-8a74c9a6c722
DOI: 10.1101/2022.03.16.484580

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Dual role of an essential HtrA2/Omi protease in the human malaria parasite: maintenance of mitochondrial homeostasis and induction of apoptosis like cell death under cellular stressDOI 10.1101/2022.03.16.484580Read

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