Article

Excess dietary sodium partially restores salt and water homeostasis caused by loss of the endoplasmic reticulum molecular chaperone, GRP170, in the mouse nephron

2024-01-14

Abstract excerpt

<h4>ABSTRACT</h4> The maintenance of fluid and electrolyte homeostasis by the kidney requires proper folding and trafficking of ion channels and transporters in kidney epithelia. Each of these processes requires a specific subset of a diverse class of proteins termed molecular chaperones. One such chaperone is GRP170, which is an Hsp70-like, endoplasmic reticulum (ER)-localized chaperone that plays roles in prote...

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Literature Corpus work: 02d9ee06-e2c5-5dcc-b3bc-44916d63190b
DOI: 10.1101/2024.01.13.575426

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