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Article

Patients with Tuberculosis Have a Dysfunctional Circulating B-Cell Compartment, Which Normalizes following Successful Treatment.

PLoS pathogens - 1 Jun 2016

Joosten Simone A, van Meijgaarden Krista E, Del Nonno Franca, Baiocchini Andrea, Petrone Linda, Vanini Valentina, Smits Hermelijn H, Palmieri Fabrizio, Goletti Delia, Ottenhoff Tom H M

Abstract excerpt

B-cells not only produce immunoglobulins and present antigens to T-cells, but also additional key roles in the immune system. Current knowledge on the role of B-cells in infections caused by intracellular bacteria is fragmentary and contradictory. We therefore analysed the phenotypical and functional properties of B-cells during infection and disease caused by Mycobacterium tuberculosis (Mtb), the bacillus...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 27304615
DOI: 10.1371/journal.ppat.1005687
PMCID: PMC4909319

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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