Article

Experimental evolution reveals post-transcriptional regulation as a novel driver of <i>Leishmania</i> fitness gain

2021-03-22

Abstract excerpt

The protozoan parasite Leishmania donovani causes fatal human visceral leishmaniasis in absence of treatment. Genome instability has been recognized as a driver in Leishmania fitness gain in response to environmental change or chemotherapy. How genome instability generates beneficial phenotypes despite potential deleterious gene dosage effects is unknown. Here we address this important open question applying exp...

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Literature Corpus work: 02c59664-db13-5319-94ab-c754cfbd0899
DOI: 10.1101/2021.03.22.436378

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