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Gene Expression in <i>Leishmania</i> Is Regulated Predominantly by Gene Dosage

13 Sept 2017

Abstract excerpt

ABSTRACT Leishmania tropica , a unicellular eukaryotic parasite present in North and East Africa, the Middle East, and the Indian subcontinent, has been linked to large outbreaks of cutaneous leishmaniasis in displaced populations in Iraq, Jordan, and Syria. Here, we report the genome sequence of this pathogen and 7,863 identified protein-coding genes, and we show that the majority of clinical isolates possess...

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PMID: 28900023
DOI: 10.1128/mbio.01393-17

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