Article

SARS-CoV-2 D614 and G614 spike variants impair neuronal synapses and exhibit differential fusion ability

2020-12-03

Abstract excerpt

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) that causes Coronavirus disease 2019 (COVID-19) exhibits two major variants based on mutations of its spike protein, i.e., the D614 prototype and G614 variant. Although neurological symptoms have been frequently reported in patients, it is still unclear whether SARS-CoV-2 impairs neuronal activity or function. Here, we show that expression of both D614 a...

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Literature Corpus work: 02b128da-b406-5c98-a1ba-801d2265d88c
DOI: 10.1101/2020.12.03.409763

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