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Spike protein mediated membrane fusion during SARS‐CoV‐2 infection

12 Oct 2022

Abstract excerpt

The pandemic caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has posed a serious threat to public health and has quickly become a global concern. The infection of SARS-CoV-2 begins with the binding of its spike protein to the receptor-angiotensin-converting enzyme 2 (ACE2), which, after a series of conformation changes, results in the fusion of viral-cell membranes and the release of the...

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PMID: 36224449
DOI: 10.1002/jmv.28212

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