Article

Slitrk/LAR-RPTP and disease-associated variants control neuronal migration in the developing mouse cortex independently of synaptic organizer activity

2023-10-20

Abstract excerpt

Slitrks and their ligands LAR-RPTPs are type I transmembrane proteins previously implicated in the etiology of various neuropsychiatric disorders including obsessive-compulsive disorders (OCDs) and schizophrenia. Over the last decade, their functions were extensively studied in hippocampal neurons in vitro and shown to shape synapse organization. Although both protein families are highly expressed prior to synaps...

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Literature Corpus work: d2b9a326-b9cd-5c2b-95e5-2349ba217d3c
DOI: 10.1101/2023.10.20.563293

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